Liquid biopsy guidelines

A term that was created in 2010 called “liquid biopsy” became the standard for much of the screening of cancer that is done using blood to check for cancer cells though the NCI definition is specific for cancer and used to include its applications in detecting cancer and determining therapeutic efficacy : https://www.cancer.gov/publications/dictionaries/cancer-terms/def/liquid-biopsy

The first one that was approved by the FDA was in 2016 for Non small cell lung cancer using EGFR mutation test v2 in plasma and since then FDA has issued guidance for the industry in 2024 that can help the industry plan for these tests.

https://www.fda.gov/media/183874/download

Similar Posts

  • Considerations for analysis of clinical samples

    When diagnostic tests are implemented in clinical studies there are multiple considerations beyond just the assay and the analyte that are not generally considered but are important. For example: Sample collection, preparation and transport Standards need to be specified for pre-analysis that would specify the conditions needed even before the analysis are done. Selection of…

  • Autism and fever

    There have been studies, that show that in a significant proportion of Autistic patients the symptoms of Autism decreases when the patients have a fever, or are treated with an antibiotic – vancomycin. This effect has been known since about 1980 and (also reported on the web at Simons foundation too). When a fever ran…

  • |

    Causes of Death

    If you’re a billionaire, then you’ve got a lot of wealth and access to our resources. However, what you do not have is access to additional years of your life.There has been a wonderful Substack post about how billionaires die. It turns out that most of the death is due to aging and unspecified reasons,…

  • Multi-cancer early detection

    There have been so many multi-cancer early detection tests coming on the market and the users are generally not aware of them – each of them have a different capability and strengths. Genomeweb had done a survey of what are the tests available and how they are perceived. Look at the survey at : https://www.genomeweb.com/cancer/genomeweb-survey-enthusiasm-mced-tests-research-and-clinical-care-despite-evidence-caveats…