Notes from the Fidelity Funders AI Week Breakfast Boston AI Week brought together a panel of biotech and healthcare investors for a morning conversation on fundraising, portfolio strategy, and how AI is actually being used in life sciences right now. Reach Out Early One of the clearest pieces of advice from the panel: don’t wait…
This was at Google’s offices in Cambridge, MA learning GCP and Google cloud framework while using AI tools for drug discovery. Thank you to the team members at Google, for helping me understand how to set up an AI workflow and discover drugs by targeting EGFR (Epidermal Growth Factor Receptor) kinase domain. This example is…
There are many AI tools for Cheminformatics and it takes a while to learn. Pat Walters has been practicing and teaching chemoinformatics and is a great resource. His GitHub page also has many tutorials. Worth a listen and read. https://github.com/PatWalters/practical_cheminformatics_tutorials
Computers and devices connect to each other through physical connections – these are the hardware ports such as Ethernet port. They also connect to each other through wireless ports. Now “computers” could mean phones, devices, sensors or anything that needs to talk to other devices/computers. These ports enable the computers to talk to each other…
Why this caught my eye I recently found Vero Bioscience, a company that says one blood draw can tell you how old each of your organs is. Not one “biological age” for your whole body, but a separate reading for your brain, heart, lungs, kidneys, liver and more. That is a bold promise, so I…
Two types of inflammatory bowel disease, Ulcerative colitis and Crohn’s disease. A challenge in IBD development is that many drugs show systemic PK and PD but fail in the intestinal mucosa. Most companies focus on Ulcerative colitis due to a) homogenous biology, b) access to tissue, c) established endpoints and d) lower variability in translational…
From the public pipeline, it appears that the interest is in vascular anomalies Hence the biomarker plan would be the following: The website is : https://relaytx.com
Biomarker plan There is a company that is developing gene therapy for Retina market and Cystic fibrosis called 4DMT. What would its Biomarker plan look like and what would the translational person do at the company? Sometimes it is clear what is needed though specific execution steps and assays can be challenging. The devil is…
In any Biotech company, there is always a promise of platform technology that enables it to produce many products. And investors and Biotech companies always consider which is the way to go – do they fund the developed of the Platform or the drug but it’s always a tossup between which is funded and which…
Biotech companies keep getting bought and sold and there are many steps that enable the transaction. A key step is the financial transaction that facilitates the sale. One company that has been incredible in facilitating the transactions is called Centerview Partners cofounded by Blair Effron and Robert A Pruzan. They have such a large variety…
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