Many pathways to hit in epigenomics to target cancer.
The picture is from this article:
Dai, W., Qiao, X., Fang, Y. et al. Epigenetics-targeted drugs: current paradigms and future challenges. Sig Transduct Target Ther 9, 332 (2024).
https://doi.org/10.1038/s41392-024-02039-0
Much of biological science and technologies are trying to cure disease. However, there are a large group of people who do not want to be cured. There are several instances and examples where they have objected vehemently about not doing things that would cure their ailment. What ailment ? Deafness. Deafness has been cured to…
Sleep apnea is when sufferer stops breathing (apnea) at night as the muscles in the throat relax and then resumes when brain semi-awakes when the oxygen supply gets low to restore respiration. This happens tens to hundreds of times at night and can be debilitating when the disruption to sleep causes other health effects such…
There are many therapies for regulating high blood pressure. The one that has received some attention is the natural therapy by consumption of beet in various forms. Juice, raw, tablets, and cooked. The primary benefit appears to be conferred by the presence of nitrates, which enhance the amount of Nitric oxide present in blood and…
Fortune highlighted Regeneron for its ability to do drug discovery for much less. To quote from their article here are the costs for drug development by some of the Big Pharma: Merck : $5.5 Billion per drug Pfizer: $7.8 Billion Sanofi: $10 Billion Average for other Pharma: $4.3 Billion Regeneron: $0.75 Billion There may be…
Response rate – using RECIST (Response evaluation criteria in solid tumors) criteria in solid tumors – the immediate response that the solid tumors had – did it grow or shrink? This is very short time duration. It is usually from the first time the imaging was done till the next time. RECIST : categories are…
Plants communicate with each other. That much is known. However, what is not known is how plants communicate using symbiosis. Dr Johnson has reported new work in Ecology letters that shows that plants use symbiotic fungi to enable communication. Communication also causes interesting secretion by plants when infected by aphids. These secretions that are volatile…
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