Neglected diseases definition?

See the link below for a disease that has affected about 100 people in the US since 1960. It is contracted by swimming in a few lakes which have sediment that can stir up amoeba. This amoeba called Naegleria Fowlerie and can infect the neurons through the nasal cavity. Eating their way through neurons from the neural cavity to the brain causes almost a complete destruction of the brain.

{youtube}9LniV6ILVXc{/youtube}

This is such a fascinating study topic since these amoeba are only found in warm lakes and they have to infect a people through their noses.

Is this a “Neglected disease”? Is this important to work on ? Yes. However, it leads to questioning what is an important disease to work on? Is a neglected disease one in which many more people are affected but still less than a full blown epidemic?

How does a scientist choose to work on a neglected disease ? How do they make a decision on the topic to work on that is important? It is possible that most scientist decide to work on a topic that pique’s their curiosity rather than label a disease – Neglected disease.

Similar Posts

  • |

    Default mode network

    When we are not focused on a task, mind-wandering or just idling, specific regions of the brain such as medial pre frontal cortex, angular gyrus, hippocampus become activated and are called the default mode network. This is thought to be important for self referential thought, memory and future planning. It has been mapped with resting…

  • ADHD

    Attention deficit hyperactivity disorder is thought to be neuro-developmental disorder that is thought to have a genetic component since it is heritable as shown from the twin and family studies. There are 3 core features that are used in diagnosis since it is not a single type of disorder but rather defined by DSM-5 classification…

  • Pharmacologically active constituents in plants

    There are many compounds in plants that are active in animals and humans. In broad category, all of these compounds listed below are listed. But, lets take it one at a time. Proanthocyanidins Cyanogenic glycosides Polysaccharides Glucosinolates Bitters Alkaloids Coumarins Saponins Phenols Volatile oils Flavonoids Tannins Anthraquinones Cardiac glycosides Proanthocyanidins: These molecules give the plants…

  • |

    Neurological conditions

    There has been changes in the neurological conditions overtime, and you might expect that many of the changes may have increased such as all the neurological disorders like Parkinson’s Alzheimer’s, but the true facts are a little different. For example, as expected, the diabetic neuropathy has increased, But what explains the increase in neonatal sepsis…

  • |

    Open source protein models

    A company called Profluent (profluent.bio) has been developing protein models that can be used for designing new proteins (https://www.nature.com/articles/s41587-022-01618-2), modeling of new CRISPR-Cas sequences (https://www.nature.com/articles/s41586-025-09298-z) and developing LLM for protein generation (https://www.biorxiv.org/content/10.1101/2025.11.12.688125v1.article-info). What is amazing is that they have open sourced all their models and Profluent-E1 is available in GitHub to download and use. (https://github.com/Profluent-AI/E1)…

  • |

    Mesoscale explorer

    Sometimes it is hard to imagine how many molecules are involved in a common biological pathway but there are thousands of molecules that orchestrate their chemical reactions to sustain life. One such area is the synaptic gap where messages are passed between neurons. This is a very active space where vesicle with messengers cross the…