Interest in longevity is increasing. There are many conferences in aging research – almost 2 a month for 2026. For a full list see here:
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AI for drug discovery
There are many companies that promise AI for drug discovery such as ChatGPT from OpenAI, Anthropic’s AI suite and Perplexity and there are more companies coming up too. One specific company that is unusual is that it seems to be promising much more deeper understanding of the drug discovery pathways then the others. It can…
Vitamin K2
It has been traditionally thought that for bone health, sufficient calcium is required. However, it is just not calcium. A vitamin called Vitamin K1 (phylloquinone) and K2 (menaquinone) in combination with Vitamin D2 and calcium is important for activating a protein called osteocalcin which binds to calcium to build bones. Osteocalcin is also involved in…
Squid camouflage
Distributed light sensing Squid can really hide well in their environment. It is important for their survival since they have minimal active defenses but how is it important to us? Office of Naval Research thought that it was important enough to grant a $ 6 million grant to Roger Hanlon of Woods Hole Marine Biological…
TDP43
TDP43 (a nuclear DNA-RNA binding protein) is involved in splicing, RNA transport and stability in neurons. It was first identified as a pyrimidine rich TAR DNA sequence in HIV type 1 gene to modulate HIV gene expression. In 95% of the ALS patients, TDP43 is abnormal located within the cell and may also be aggregated,…
LDH – lactose dehydrogenase
LDH (Lactose dehyrogenase) is a biomarker for tissue injury or cell lysis anywhere in the body. Typically it was used for heart damage during myocardial infarction where it was a cardiac necrosis marker. It is also possible that it is a liver disease biomarker that shows liver injury by itself or in cancer metastasis. In…
