Drug delivery to the human body is complicated business. It seems to the average consumer that they only have to take the pill and the API (Active pharmaceutical ingredient) magically does the work in the body. However, things are complicated when the API is not soluble. Drug delivery scientists spend significant amounts of time to…
There was once a company that engineered a very good sensor . This sensor measured whether you were sitting up straight in your chair or slouching. If you slouched it sent a small vibration and reminded you. The market need that they targeted was that people needed to sit straight for their back and this…
There have been several studies that show that innovative trial design is required and in August 2018, FDA launched a program that would encourage novel clinical trial designs. They have issued guidance on novel trial design such as an expansion cohort which seeks to expand the clinical trial by allowing various cohorts into early phases…
The term is more complex than the function! Synthetic biology implies control of biological circuits through a control mechanism. Wikipedia calls it “redesign of existing biological systems for useful purposes”. This combines biology and engineering and the differentiator between yeast based beer making might be the control systems that are built in the system by…
Recently we have been studying human walking and trying to understand its various components.Human walking seems so simple as shown in the video below by phsiotutors, but is a very complex activity. It involves multiple muscle movements coordinated into a seamless activity that is a balancing act on two legs accompanied by forward motion. Walking…
We had an interesting discussion with Dr Rebecca Fitzgerald, MD who is a Professor of Cancer Prevention at the University of Cambridge. Dr Fitzgeralds work aims to improve methods for early cancer detection for esophageal cancer through better understanding of the methods of molecular pathogenesis.She has developed many methods to quantify biomarkers in Barrett’s syndrome….
There has been significant discussion on who owns medical data. The hospital or service that collects the data or the patients themselves? Then there are questions about how do we manage the data – who manages the data? Security issues? Exchange and storage? And more importantly business issues on who commercializes the data – who…
Wearable for digital health requires communication strategy: IOT and LORAWANAn ideal wearable digital health system has these 3 top requirements:1. Simple – No complicated setup and automated data collection procedure 2. Long measurement – Ability to collect data over extended periods3. Actionable data that is securely stored or sent to a databaseDigital health technologies have…
Many research studies have incorporated the use of wearable devices into the study to measure the activity of humans in response to a variety of interventions. There are grossly three parts to that process:1. Selection and adoption of the activity monitor – accelerometer or gyroscope based devices2. Process for collection of the data – supervised…
Since the time the first IQ test was developed in 1904 by Alfred Binet, there has been a continuous search for a way to predict and quantify human intelligence. The methods have ranged from measuring the diameter or volume of the head to more complex methods of today using imaging methods such as fMRI….
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