Try moving molecules now!
Isn’t this beautiful? It shows the structure of the mechanosensitive Piezo1 channel with display from NIH system – https://www.ncbi.nlm.nih.gov/Structure/icn3d/full.html
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Virtual cell
Hani Goodrazi – Arc institute has been working on virtual cell. Drugs fail due to overfit experimental models, You need screen drugs with better models of human biology. Geneva is platfrom that brings tumor models into perturbation model – that is a transcriptomics assay that deconvolves into effect. Take multiple cell line and then treat…
Noetik – Data driven models
Came across an interesting company called Noetik.ai https://www.noetik.ai/ Their platform and models are using spatial biology data to develop AI models that could help in drug discovery. They have partnered with GSK to in Colorectal cancer and Non small cell lung cancer and GSK will license their OCTO models for their research. The image is…
Mesoscale explorer
Sometimes it is hard to imagine how many molecules are involved in a common biological pathway but there are thousands of molecules that orchestrate their chemical reactions to sustain life. One such area is the synaptic gap where messages are passed between neurons. This is a very active space where vesicle with messengers cross the…
