News

  • ADHD

    Attention deficit hyperactivity disorder is thought to be neuro-developmental disorder that is thought to have a genetic component since it is heritable as shown from the twin and family studies. There are 3 core features that are used in diagnosis since it is not a single type of disorder but rather defined by DSM-5 classification…

  • Heart valve

    Heart valve failure symptoms are shortness of breath, fatigue, swollen legs etc and usually you can see on the ultrasound. Calcium deposits are the main reason for heart valve failure. This blockage of the valve is called stenosis.This is mainly an age related disability and diet or other modifications will not affect their progression. Typically…

  • Grunost

    Grunost is a type of cheese that is sweet and often typical of Norways’ cheese culture. It is incidentally not a cheese at all since it is made from the process of making cheese that leaves whey as a by product. This whey is boiled with milk or cream to make a brown caramelized cheese….

  • Capsaicin

    Capsaicin is the flavoring and key ingredient for the heat in chili peppers. The heat comes from its interaction with TRPV1 (vanilloid receptor subtype 1) ion channel that leads to the burning sensation in any animal tissue that comes into contact with it. Interestingly, bird TRPV1 is not responsive to capsaicin. Another function that has…

  • Garlic crush and sit rule

    More about garlic preparation. Garlin contains alliin stored in the cytoplasm which is converted by enzyme allinase, which is in the cell sap, to allicin which is the key sulfur compound responsible for its flavor and all the health benefits. However to make the enzyme react, the crushing process needs to take place at room…

  • Explainable AI

    A very traditional problem solving method is the following: given a set of features or variables, can we understand the features to form a conclusion. This could be something like a treatment strategy wherein the strategy is built on a series of data and then ingesting the data helps make a conclusion. However, an equally…

  • Biotech clusters

    Biotech cluster in Boston/Cambridge Kendall square has become a hub of new Biotech companies. The one developer that has had a major role to play has been David Clem who’s effort has been documented by Robin Wolfe Scheffler – a MIT historian and author of David Clem: Building Genetown. This model is not easy to…

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    TDP43

    TDP43 (a nuclear DNA-RNA binding protein) is involved in splicing, RNA transport and stability in neurons. It was first identified as a pyrimidine rich TAR DNA sequence in HIV type 1 gene to modulate HIV gene expression. In 95% of the ALS patients, TDP43 is abnormal located within the cell and may also be aggregated,…

  • LoRa adaptors

    LoRa in the IOT community are the low power long range wireless standards devices that are utilized to send a signal over large distances. However, in the AI field LoRa implies Low rank adaptation – which is relatively more efficient compute way to fine tune pretrained models (LLM, vision transformers, diffusion models). With a pretrained…

  • Flow

    The father of focus was Mihaly Csikszentmihalyi an American Hungarian psychiatrist who associated focus with happiness. His contention was that true happiness comes from doing things in flow. Flow was designed as something that had enough challenge that makes it exciting while at the same time not being boring. For example, passive activities such as…