Transferring any protein, DNA or a large molecule through the cell is very difficult. There are two techniques that are very commonly used for this purpose. The one that is used the most in electroporation: in which a defined pulse of current /electricity is passed through the medium to create small holes in the membrane…
The gold standard for almost all the paper based diagnostic tests is the home pregnancy test called Clear Blue. What is forgotten is that this test was created in 1985 by a company called Unipath and this went on to become the most often used test that became a standard by which most diagnostic tests…
It is hard to imagine binding forces as a scientist develops an immune-assay and often times the commonly used antibodies are often thought to be the tightest binders. But these forces are very interesting to measure and compare among different types of interactions. But first what is the measurement unit of the force? The force…
Dr Singamaneni’s from the University of Washington in St. Louis has created interesting and bright reporter molecules that could function as next generation probes for Biomarkers. Typically, the probes used are fluorescent or heavy metal but rarely have used Raman scattering for for pre-clinical assay work. The phenomenon is very interesting since it uses Surface…
Ushio has made a great detector that can detect toxins, drugs and many other agents using a new method of detection that was published earlier in 2011. The technology is interesting. The detection reagent is a Variable region fragment ofHeavy chain antibody (VH) that has the quenched fluorescence group embedded in its structure. This is…
This is an unusual strategy adopted by only a few companies. The company believes in its strategy, instrument, device or service so much that it essentially tells the customer, we are different and we would like to stay that way. Join us if you like us otherwise we do not care. This is a tough…
Vanadium Dioxide is an interesting material. It functions as a metal at some temperatures and then as an insulator at other temperatures. The microscopic reason for the transition is unknown but the ways this can be used is interesting. Transition metal oxides make for interesting studies. They are normally an insulator that does not allow…
Dr Hagan Bayley’s lab has been working on ion channels, pores and droplet based technologies. Dr Gabriel Villar from that group just published a paper in Science that shows the formation of unique droplets submerged in hydrocarbons/oil. The formation of these droplets is interesting but what is unique is that they can form interactions amongst…
Changing the perspective is always difficult. It is hard to imagine how the perspective can be changed in a standard product that is off the shelf but often times it works significantly if the same device or instrument is used in a unique or different way. Let’s go back to the example of a centrifuge…
Many visitors come to Philadelphia to learn about American history and make a compulsory stop to see the Liberty Bell. However, what is relatively unknown to most of them is that there is a great chemical technology library, museum and a center for scholars less than three blocks away called the Chemical Heritage Foundation. There…
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