Mindblown: a blog about philosophy.
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Supply and demand: Synthetic urine
It is just amazing how supply follows the need and if the need is urine then businessmen will supply urine – even if it is fake urine – called synthetic urine.The need for urine is for drug tests. When a person undergoes a drug test, they typically need to supply their urine and this urine…
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Which technologies will succeed? Make it simple and they will come…
Most of the studies that predict which books will be a hit, which tweet will get the most attention and what social media post will go “viral” have not been very successful. There have been many studies to understand and evaluate which technologies will succeed and which of those will fail. These studies hope to…
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Drug delivery and excipients
Drug delivery to the human body is complicated business. It seems to the average consumer that they only have to take the pill and the API (Active pharmaceutical ingredient) magically does the work in the body. However, things are complicated when the API is not soluble. Drug delivery scientists spend significant amounts of time to…
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One Danger of working with digital health companies
There was once a company that engineered a very good sensor . This sensor measured whether you were sitting up straight in your chair or slouching. If you slouched it sent a small vibration and reminded you. The market need that they targeted was that people needed to sit straight for their back and this…
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Innovative clinical trial design
There have been several studies that show that innovative trial design is required and in August 2018, FDA launched a program that would encourage novel clinical trial designs. They have issued guidance on novel trial design such as an expansion cohort which seeks to expand the clinical trial by allowing various cohorts into early phases…
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Synthetic biology
The term is more complex than the function! Synthetic biology implies control of biological circuits through a control mechanism. Wikipedia calls it “redesign of existing biological systems for useful purposes”. This combines biology and engineering and the differentiator between yeast based beer making might be the control systems that are built in the system by…
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Measuring gait
Recently we have been studying human walking and trying to understand its various components.Human walking seems so simple as shown in the video below by phsiotutors, but is a very complex activity. It involves multiple muscle movements coordinated into a seamless activity that is a balancing act on two legs accompanied by forward motion. Walking…
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Developing a simple device and a Biomarker takes effort
We had an interesting discussion with Dr Rebecca Fitzgerald, MD who is a Professor of Cancer Prevention at the University of Cambridge. Dr Fitzgeralds work aims to improve methods for early cancer detection for esophageal cancer through better understanding of the methods of molecular pathogenesis.She has developed many methods to quantify biomarkers in Barrett’s syndrome.…
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Pictures and photo as paradigm for medical data
There has been significant discussion on who owns medical data. The hospital or service that collects the data or the patients themselves? Then there are questions about how do we manage the data – who manages the data? Security issues? Exchange and storage? And more importantly business issues on who commercializes the data – who…
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Wearable for digital health requires communication strategy: IOT and LORAWAN
Wearable for digital health requires communication strategy: IOT and LORAWANAn ideal wearable digital health system has these 3 top requirements:1. Simple – No complicated setup and automated data collection procedure 2. Long measurement – Ability to collect data over extended periods3. Actionable data that is securely stored or sent to a databaseDigital health technologies have…
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