NF1 – major optic glioama Half of them will be affected and others not. The eye is affected even though glioma’s are not life threatening. The tumor and eye will not be matched in some cases. Visual acuity – Vision develops in childhood – they do not see 20/20 till they are 6 years old….
LDH (Lactose dehyrogenase) is a biomarker for tissue injury or cell lysis anywhere in the body. Typically it was used for heart damage during myocardial infarction where it was a cardiac necrosis marker. It is also possible that it is a liver disease biomarker that shows liver injury by itself or in cancer metastasis. In…
Pricing is an important factor of all business. Every business tries to make a decision on how best to set its prices and there are so many variables that the company must consider to make a decision. Consider a few approaches. The simplest approach is adding a profit factor to the cost and using that…
This is an approach to design polymers that recognize materials which may be of biological origin. Their advantage is their high selectivity and affinity for the target molecule. The high level view of the process to create such a polymer is relatively simple though the devil may be in the details. In the presence of…
Bile duct cancer or cholangiocarcinoma, (CCA) is a rare cancer with an incidence of ~3 cases per 100,000 with 10,000 new case diagnosed annually. It is about 10-20% of liver cancers. Interestingly, in Thailand, and some south east asian countries, the incidence is nearly 10 fold higher due to liver fluke infections (Opisthorchis viverrini and…
In alligator length estimation, the snout-eye-length is an approximation of length used for some species and speaks about proportionality of growth. For example, each inch length from the eye of the crocodile to the end of the snout equals the length of the alligator. For example 3 inches of snout-eye-length implies that the alligator is…
It has been traditionally thought that for bone health, sufficient calcium is required. However, it is just not calcium. A vitamin called Vitamin K1 (phylloquinone) and K2 (menaquinone) in combination with Vitamin D2 and calcium is important for activating a protein called osteocalcin which binds to calcium to build bones. Osteocalcin is also involved in…
There is lot of information on BPA on wikipedia that talks about its use in plastics especially polycarbonates that are used in water bottle manufacturing. Polycarbonate bottles are transparent and can contain 90% BPA by mass It is not a plasticizer. The concern for its use comes from its effect as a weak xenoestrogen disrupting…
There are many therapies for regulating high blood pressure. The one that has received some attention is the natural therapy by consumption of beet in various forms. Juice, raw, tablets, and cooked. The primary benefit appears to be conferred by the presence of nitrates, which enhance the amount of Nitric oxide present in blood and…
Staccato comments on cardiovascular disease Heart attack – Most common reason is blockage but not every time. Angina is progressive blockage that is causing heart attack. EKG often times cannot show a heart attack. It shows 60-70% of time but not 100%. You don’t wait for the enzymes to go up in an emergency. Many…
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