Mindblown: a blog about philosophy.

  • Applications for mobile phones : FDA cleared EKG

    Electrocardiogram (ECG) has typically been done with an 12 lead device that measures the change in voltage at different terminals. This machine is rugged and sensitive to other signals. However, disruption of this technology is happening from small iPhone based devices that record ECG using just two sensors that are placed behind the phone. A…

  • Image based Phenotypic screening

    When screening for phenotypes there are many methods that are used. Usin’Life uses artificial intelligence methods to analyze the image data sets but there have other laboratories that use other interesting methods. Dr Lu’s lab published a paper in Nature methods (Nat. Methods 9, 977–980, 2012) that uses microfluidic technology to determine the phenotypic characteristics…

  • Medical software development – Finite state machines

    Food and Drug Administration (FDA) regulates significant portion of medically relevant devices and drugs but it is probably not as well known that they also regulate the software that is used to power many of the studies. There are significant guidelines from FDA that are used for manufacturers of software that regulate medical devices. The…

  • Mobile applications: Fluorescence spectra.

    Usin’Life is working on developing a mobile applications for fluorescence spectra observation. Typically, the android market has several applications that show the spectra but they are very company specific. This makes a user struggle to find the spectra of interest. If they have access to the computer then one way to do this is to…

  • Mobile applications: Terahertz –CMOS combination.

    This is work in progress since a mobile phone with terahertz capability does not exist yet but could potentially be very useful. Terahertz waves are those in the electromagnetic spectrum that are between millimeter waves and infrared, with frequencies between 0.3 to 3 Terahertz. Currently the technology to generate and analyze them do not exist…

  • Creating heavy metal mass spectrometry libraries as bar codes for cells

    Fluorescence technologies with flow cytometry have been used in the clinical sciences for many purposes since it has been established method. This is standardized for clinical analysis but also for other research based applications. It however suffers from one limitation that it is limited to 20 independent channels and is very complex to setup 20…

  • Lifestraw – simple device that is very useful.

    People in developed countries fail to realize the problems that face citizens of countries that have to fight to get pure water to drink. There have been a few technologies for that but the easiest one has been the use of a Lifestraw made by a company called Vestergaard Frandsen. The specifications are impressive: it…

  • LED market as example – Invest in R&D

    LED have been used in all applications in electronics and also in imaging for providing long lasting consistent illumination, as well as indicators in instruments but only recently have started entering the market as home lights. UK based IMS Research publishes reports that estimate the market for packaged LED’s and they have estimated the market…

  • Applications for mobile phones : Microscopes

    Keeploop has an interesting idea on combining an additional lens and LED into a compact device that is attached magnetically onto the back of the phone on top of the camera lens in a mobile phone. This increases the magnification of the phone lens and also enables to work in a macro mode. This macro-lens,…

  • Phenotypic drug discovery – Sirturo – Tuberculosis compound from Janssen

    Drug Discovery is expensive and many pharmaceutical companies make sure that the process is followed through all the steps including the ability to get their investment back from drug discovery. Janssen just got the FDA approval for tuberculosis. However, their motive was very different. There are only few hundred patients with drug resistant TB (tuberculosis)…

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