Mindblown: a blog about philosophy.

  • Which Pharma company stock to buy?

    This question can be analyzed an-infinitum but the real answer is simple. Each of the Pharma companies here grows by their ability to research new drugs and chemical compounds. The more they spend on research, the better they will perform moving forward. The chart below is a percentage of what these companies spend on R&D…

  • Pharmaceutical company sales

    It is surprising how few pharmaceutical companies are left that are big companies with large R&D Budgets, but the top 50 Pharma companies has very few surprises from the usual suspects. Take a look at the chart below that is derived from the Pharma Exec (link below) data. Interesting conclusions can be drawn from the…

  • Developing software for FDA certification.

    When a company buys and uses software that is off the shelf software, like the Windows operating system there is still some responsibility to the developer to check that the software works as it is supposed to work. With other pieces of software, say the National Instruments – LabView that is incorporated into more medical…

  • Device to measure tablet hardness

    Almost everything can be quantitated. It is interesting to see how devices are created to measure things accurately. Consider measuring tablet hardness. This is a quantifiable parameter. It is important from the dosage and breakage point of view but also important to measure how the tablet making machines and the various binders are working efficiently.…

  • Food science – wasabi and snakes

    It is amazing how much thought and science goes into producing food substances that we take for granted. The real wasabi owes its fiery nature to a volatile chemical called allyl isothiocyanate that binds to specific receptor in humans called TRPA1 – (Transient receptor potential) that is activated by heat in some instances. This allyl…

  • McGurk effect – you actually hear only what you see or want to hear!

    The video below explains it all. But essentially our perception is dependent on what we see. Wonder how many of these effects exist without us realizing it {youtube}FefFfvriAwQ{/youtube}

  • Single cell addresses

    When we think of internet, it seems amazing to see that there are so many computers connected. This was made possible by the internet protocol version 4 provides 232 (4,294,967,296) addresses even though not all of them are usable. There are mostly saturated and the total number becomes about 4.2 billion and that is about…

  • Electronic lab notebook (ELN) comparison

    The lab is an important place where discoveries are made, whether the lab is virtual or whether the lab is a physical space where experiments are conducted. It is also a place where the data is acquired, compared and finally conclusions drawn to make the discoveries possible. One feature that is common to most labs…

  • Controls and standards for fluorescence

    There have been many ways that people use standards for fluorescence but the one big one that has been used in flow cytometry and imaging. The one area that has developed a lot is the use of plastic fluorescent beads as controls. There are obviously many companies that have developed that but the one company…

  • Strange old tales that may have a basis in medicine:

    There are several things that were considered odd by western medicine but have been proven much later to be useful. Consider these two examples: Stitches during surgery: In Kenya, Uganda and parts of South Africa, doctors or sham-doctors used ants to treat a wound. This was considered odd by western medicine. However, what is interesting…

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