Category: Imaging

  • Bug eyes with camera

    It is known that eyes of the common fly is a compound eye with multiple detectors and multiple lenses. It has always been thought that the 180 degree vision would be very useful and could be very high resolution. Though interesting to think about in terms of camera’s, it has been difficult to create multiple…

  • Imaging in the microwave to pick strawberries

    Robert Dudley was trying to design a system that would pick out the ripe cauliflowers that were ripe amidst the leaves. However, he ended up discovering a system that can decide when the strawberries are ripe for picking. His system uses imaging with microwave, light and terahertz radiation. He found that the microwave radiation, that…

  • Controls and standards for fluorescence

    There have been many ways that people use standards for fluorescence but the one big one that has been used in flow cytometry and imaging. The one area that has developed a lot is the use of plastic fluorescent beads as controls. There are obviously many companies that have developed that but the one company…

  • Differential interference contrast microscopy

    Looking at samples under a microscope that are unstained typically shows nothing. Without a stain to show the sample, most specimens would look invisible and transparent. However, one technique that has been used in microscopes for a very long time is called differential interference contrast (DIC) microscopy and is dependent on a very simple principle.…

  • Persistent Luminescent phosphors encourage formation of reefs

    Luminescent phosphors have been used in biology and imaging for many applications. Interestingly, there is another application that has not been publicized as much. Scientists from Malaysia, Moldova and Russia have made unique persistent phosphors that last for many days and hours in tough environment below the ocean. These are originally made nearly 16 years…

  • Soft nanomaterials, Raman scattering and BRIGHTS

    Dr Singamaneni’s from the University of Washington in St. Louis has created interesting and bright reporter molecules that could function as next generation probes for Biomarkers. Typically, the probes used are fluorescent or heavy metal but rarely have used Raman scattering for for pre-clinical assay work. The phenomenon is very interesting since it uses Surface…

  • Confocal microscopy trending

    When you look at this Google trends chart below that is looking for “Confocal microscopy”, what thoughts come to your mind? Is this something that you would want to do or is this something so specialized that it has only limited interest? Or what about the distribution through the world? Is US the only one…

  • Membrane permeant probes for infrared imaging

    Dr Kai Johnsson has been working in the area of super resolution imaging and has come up with some very useful fluorescent probes for glutamate, switchable flourophores for protein labeling, caged rhodamine derivates among other research on membrane biology. His group just showed another interesting probe that can go inside the membrane and can be…

  • Image based Phenotypic screening

    When screening for phenotypes there are many methods that are used. Usin’Life uses artificial intelligence methods to analyze the image data sets but there have other laboratories that use other interesting methods. Dr Lu’s lab published a paper in Nature methods (Nat. Methods 9, 977–980, 2012) that uses microfluidic technology to determine the phenotypic characteristics…

  • Gigapixel camera

    David Brady of Duke University published a paper in Nature in 2012 (Brady DJ, Nature 486, 386) on 50 Gigapixel camera. The technology was interesting in that it used small camera’s that were coupled through a big lens. This may be a good strategy to make large cameras rather than depend on major lenses and…