There are large data-sets that are being generated that are amazingly large, completely open for anyone to use and see and can generate valuable conclusions.
Hapmap is one such grand project. This is made up of participants from US, UK, China, Japan, Canada and Nigeria. Look at the link below to get all the information about this NIH project that makes great bulk of data available to just about anyone with an internet connection. This is a database and haplotype map of human populations. It enables one to look at haplotypes for specific genetic traits across different populations of humans. This project has been mapping SNP (small nuclear polymorphisms) and cataloging them in many populations. The interesting part is to make sense of this big data and separate the signal from the noise.
There are going to be lot of changes between populations and it needs to be determined what would be the abnormality that is unusual vs just a random mutation.
The interesting aspect of this dataset is that there is a lot of information available and it needs to be analyzed by various entities and correlated with their projects to make sense of this data.
Here is a large freely available dataset ripe for data mining operation.